High Incidence of Psychopharmacologic Treatment Failure in Bipolar Disorder
Patients with bipolar disorder experience a high incidence of first-year treatment failure, according to cohort study data published in the Journal of Affective Disorders. However, no significant...
View ArticlePerformance-Based Measures of Functional Capacity Correlated With Objective...
Performance-based measures of functional capacity correlated with objective cognitive outcomes in patients with bipolar disorder, according to study data published in the Journal of Affective...
View ArticleTargeting Psychosis, Depression, Cognition May Improve Functional Outcomes in...
Patients with lifetime psychosis, subthreshold depressive symptoms, and poor cognitive performance are less likely to achieve functional recovery in bipolar disorder (BD), according to study results...
View ArticleCariprazine Shows Efficacy for Bipolar Mania With Mixed Features
The use of cariprazine significantly improved manic and depressive symptoms in patients with bipolar mania with mixed features, according to results from a study published in the Journal of Affective...
View ArticleLithium Effective in Treating Youth With Bipolar Disorder
In children and adolescents with bipolar disorder, lithium use was associated with fewer suicide attempts, fewer subthreshold depression symptoms, better psychosocial function, and less...
View ArticleCognitive, Functional Remediation Show Promise in Bipolar Disorder
Results of a recent study published in the Journal of Affective Disorders support the use of cognitive remediation (CR)/functional remediation (FR) in patients with bipolar disorder, with evidence of...
View ArticleSex, Higher Illness Severity Associated With Bipolar Disorder II
A study designed to determine differential characteristics between bipolar disorder (BD)-I and BD-II and published in Psychiatry Research found that being female, having a family history of...
View ArticleParental Bipolar Disorder May Affect Presentation of Pediatric Bipolar Disorder
Youth with pediatric bipolar disorder were more likely to have comorbid attention-deficit/hyperactivity disorder (ADHD) if they had a parent with bipolar disorder, according to study data published in...
View ArticleEnhanced Cortical Androgen Action Noted in Bipolar Disorder
The relationship between low testosterone and greater negative symptoms in men with schizophrenia, and a greater prevalence of anxiety and depressive disorders in men, prompted researchers to...
View ArticleAntibody Titers to Cytomegalovirus, Toxoplasma Linked to Bipolar Disorder
According to study data published in JAMA Psychiatry, bipolar disorder was associated with increased long-term antibody response to cytomegalovirus (CMV) and decreased long-term antibody response to...
View ArticleRapid Cycling Bipolar Disorder Associated With Hospitalization and Female Gender
Hospitalization, prevalent polarity, and female gender were found to increase the risk for rapid cycling in bipolar disorder, according to a study published in European Psychiatry based on data from...
View ArticleBipolar Disorder Associated With Increased Risk for Parkinson Disease
Compared with the general population, patients with bipolar disorder (BD) have an increased risk of developing idiopathic Parkinson disease (PD), study results published in JAMA Neurology suggest....
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Taro Recalls Lamotrigine After Cross-Contamination With Hypertension Drug
Taro Pharmaceuticals announced the voluntary recall of 1 lot of lamotrigine 100mg tablets to the consumer level due to cross-contamination with a small amount of enalapril maleate. The recalled lot,...
View ArticleFamily Therapy Aids Youth at High Risk for Bipolar Disorder
HealthDay News — Among symptomatic youths at high risk for bipolar disorder, times between mood episodes are longer for those receiving family-focused therapy (FFT) compared with enhanced usual care,...
View ArticleComorbid PTSD Raises Risk for Suicidal Ideation in Patients with Bipolar...
Patients with bipolar disorder have a significantly elevated risk for suicidal ideation when they experience comorbid posttraumatic stress disorder (PTSD), according to study results published in the...
View ArticleNo Evidence of Links Between Olfactory Dysfunction and Bipolar Disorder
A literature review published in the Journal of Affective Disorders failed to draw a solid conclusion about the role of olfactory deficits as a marker in bipolar disorder (BD) because of the...
View ArticleAdjunctive Dextromethorphan and Memantine May Raise BDNF Levels in Bipolar II...
Treating patients who have bipolar II disorder (BD-II) with a combination of add-on dextromethorphan 30 mg/day and memantine 5 mg/day (DM30+MM5) is significantly more effective than placebo for...
View ArticleResults of HOPE-BD Study Emphasize Importance of Early Intervention in...
An analysis of data from the naturalistic Health Outcomes and Patient Evaluations in Bipolar Disorder (HOPE-BD) study reinforces the importance of early diagnosis and interventions in patients with...
View ArticleNature or Nurture: Cross-Generational Transmission of Major Psychiatric...
Genes appear to play an overwhelming role in the transmission of bipolar disorder across generations, as well as cross-generational transmission between bipolar disorder and disorders on the...
View ArticleHigh Polygenic Scores for Depression Predicts Poorer Response to Lithium in...
A high genetic load for major depression may predict an unfavorable long term response to lithium in patients with bipolar disorder, according to findings published in Molecular Psychiatry. Only a...
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